Complex network of RNA-protein interactions regulates post-transcriptional gene expression. RNA metabolism is particularly complex in neurons, involving extensive diversification of gene expression through splicing and redistribution of RNA subsets to the distant compartments where they ultimately function. In recent years, perturbation of RNA metabolism has emerged as a consistent underlying defect in certain neurological diseases, suggesting that aspects of RNA metabolism that are unique to the nervous system may also create unique vulnerabilities.
This two-day symposium organized by Paul Taylor and Fen-Biao Gao will bring together basic and clinical scientists to discuss the role of perturbed RNA metabolism in neurological diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), spinal muscular atrophy (SMA), fragile X syndrome and other repeat expansion disorders.
Using Elsevier's new BRAIN2015 app, you can browse the scientific programme by days, topic or speaker, create your own personal programme, locate rooms and exhibitor stands on the floor plans, and more. Before first use, you will need to download the latest conference data and then afterwards, you can use the app offline.
- September 27, 2015 Initial release